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Structure of 1074-38-0
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5-Methyl-2-nitropyridine features a nitro group at the 2-position and a methyl substituent at the 5-position of the pyridine ring, creating a strongly electron-deficient heteroaromatic system. This configuration enhances reactivity in nucleophilic substitution and metal-catalyzed coupling processes. The compound exhibits bench-stable handling characteristics and serves as a key building block in pharmaceutical intermediates and agrochemical synthesis.
5-Methyl-2-nitropyridine serves as a versatile building block in synthetic organic chemistry, enabling the construction of functionalized heterocycles via selective nitro group reduction and subsequent coupling reactions. Its methyl and nitro substituents provide orthogonal reactivity for downstream modifications, including nucleophilic substitution and transition-metal-catalyzed cross-couplings. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: