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Structure of 1073182-87-2
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3-Amino-4,6-dichloropicolinic acid features a strategically positioned amino group flanked by two chlorine atoms on the picolinic acid scaffold. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced solubility and metabolic stability in bioactive molecule design.
3-Amino-4,6-dichloropicolinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its orthogonal functional groups—amino and carboxylic acid—facilitate diverse transformations including amidation, coupling reactions, and cyclization. The electron-withdrawing dichloro substituents enhance reactivity in electrophilic substitution and improve metabolic stability in downstream candidates. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: