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CS-W001157 4
Total: USD 88.00

4-(Methylthio)phenol

  • CAS No. 1073-72-9

  • Cat. No. CS-W001072
  • Purity≥98%
  • MDL No.MFCD00002351

*For research and further manufacturing use only, not for direct human use.

4-(Methylthio)phenol|CS-W001072

Structure of 1073-72-9

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General Information

  • CAS No. 1073-72-9
  • Cat. No. CS-W001072
  • Purity ≥98%
  • MDL No. MFCD00002351
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈OS
  • Molecular Weight None
  • Synonym(s) p-Methyl Thiophenol
  • SMILES CSC1=CC=C(O)C=C1

Description

4-(Methylmercapto)phenol (4MP) mediates the removal of benzyloxycarbonyl and O-benzyl protecting groups by accepting the benzyl groups during the acidolytic cleavage with trifluoroacetic acid. The presence of hydroxyl group in the para position enhances the rate of hydrodesulfurization (HDS) of 4MP.4-(Methylmercapto)phenol [4-(Methylthio)phenol] may be used in the preparation of phosphoramidodithioate intermediates for the synthesis of sulprofos amidate.

Synthesis

  • Route1

    References

    • Zhu, Chen; Wang, Rui; Falck Organic Letters, 2012 , vol. 14, # 13 p. 3494 - 3497
  • Route2
    • null|null
      637-89-8
    • null|null
      74-88-4
    • ~%
    • In-stock
      4-(Methylthio)phenol|CS-W001072
      1073-72-9

    References

    • Australian Journal of Chemistry, , vol. 59, # 4 p. 277 - 282
  • Route3
    • null|null
      540-38-5
    • In-stock
      Dimethyl sulfoxide|CS-0996365
      67-68-5
    • ~78%
    • In-stock
      4-(Methylthio)phenol|CS-W001072
      1073-72-9

    References

    • Joseph, P.J. Amal; Priyadarshini; Kantam, M. Lakshmi; Sreedhar Tetrahedron, 2013 , vol. 69, # 38 p. 8276 - 8283

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: 3335
Class : 9
Packing Group : Ⅲ
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.1141
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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