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CS-W001157 4
Total: USD 88.00

(3-Chloro-4-formylphenyl)boronic acid

  • CAS No. 1072952-53-4

  • Cat. No. CS-0174409
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3-Chloro-4-formylphenyl)boronic acid|CS-0174409

Structure of 1072952-53-4

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General Information

  • CAS No. 1072952-53-4
  • Cat. No. CS-0174409
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BClO₃
  • Molecular Weight 184.38
  • Synonym(s) 3-Chloro-4-formylphenylboronic acid
  • SMILES O=CC1=C(Cl)C=C(B(O)O)C=C1

Description

This boronate moiety features a chloro-substituted aromatic ring with a formyl group at the para position, enabling direct integration into Suzuki-Miyaura coupling reactions. The electron-deficient aryl system enhances reactivity while maintaining bench-stable handling under standard conditions.

Application

(3-Chloro-4-formylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling the efficient construction of biaryl scaffolds under mild conditions. The ortho-chloro and aldehyde functionalities provide orthogonal reactivity for downstream modifications, including nucleophilic additions and condensation reactions. Its bench-stable nature and compatibility with diverse reaction environments facilitate streamlined synthesis of complex aromatic systems.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   -0.1677
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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