Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

tert-Butyl 4-(aminomethyl)benzoate

  • CAS No. 107045-28-3

  • Cat. No. CS-0139645
  • Purity≥97%
  • MDL No.MFCD04973451

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(aminomethyl)benzoate|CS-0139645

Structure of 107045-28-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 107045-28-3
  • Cat. No. CS-0139645
  • Purity ≥97%
  • MDL No. MFCD04973451
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇NO₂
  • Molecular Weight None
  • Synonym(s) 1,1-dimethylethyl 4-(aminomethyl)benzoate
  • SMILES O=C(OC(C)(C)C)C1=CC=C(CN)C=C1

Description

tert-Butyl 4-(aminomethyl)benzoate features a robust tert-butyl ester group paired with a primary amine tethered to a para-substituted benzene ring. This combination enables direct functionalization in peptide coupling and bioconjugation workflows, offering enhanced solubility and stability under standard conditions.

Application

tert-Butyl 4-(aminomethyl)benzoate serves as a versatile building block in medicinal chemistry, enabling efficient access to biaryl and heterocyclic scaffolds. The benzylic amine functionality exhibits robust reactivity in standard coupling reactions, while the tert-butyl ester group offers excellent bench stability and convenient deprotection under mild acidic conditions. Its compatibility with diverse functional groups facilitates straightforward incorporation into complex molecular architectures.

Synthesis

  • Route1

    References

    • Ren, Sumei; McNamara, Paul; Koharski, David; Hesk, David; Borges, Scott Journal of Labelled Compounds and Radiopharmaceuticals, 2009 , vol. 52, # 8 p. 316 - 323
  • Route2
    • tert-Butyl 4-cyanobenzoate|CS-0210175
      55696-50-9
    • ~92%
    • In-stock
      tert-Butyl 4-(aminomethyl)benzoate|CS-0139645
      107045-28-3

    References

    • Nasim, Shama; Guzman, Monica L.; Jordan, Craig T.; Crooks, Peter A. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 16 p. 4879 - 4883
  • Route3
    • 4-(Aminomethyl)benzoic acid Tranexamic Impurity|CS-0229695
      56-91-7
    • ~%
    • In-stock
      tert-Butyl 4-(aminomethyl)benzoate|CS-0139645
      107045-28-3

    References

    • Ren, Sumei; Mcnamara, Paul; Koharski, David; Hesk, David; Borges, Scott Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 5-6 p. 395 - 398

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   52.32
  • LogP   2.1006
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • tert-Butyl 4-(aminomethyl)benzoate sigmatert-Butyl 4-(aminomethyl)benzoate manufacturertert-Butyl 4-(aminomethyl)benzoate pricetert-Butyl 4-(aminomethyl)benzoate structuretert-Butyl 4-(aminomethyl)benzoate SDSbuy tert-Butyl 4-(aminomethyl)benzoatetert-Butyl 4-(aminomethyl)benzoate suppliertert-Butyl 4-(aminomethyl)benzoate usestert-Butyl 4-(aminomethyl)benzoate molecular weightprice of tert-Butyl 4-(aminomethyl)benzoatetert-Butyl 4-(aminomethyl)benzoate chemical name formula of tert-Butyl 4-(aminomethyl)benzoate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label