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CS-W001157 4
Total: USD 88.00

Acethydrazide

  • CAS No. 1068-57-1

  • Cat. No. CS-D1403
  • Purity≥95%
  • MDL No.MFCD00007610

*For research and further manufacturing use only, not for direct human use.

Acethydrazide|CS-D1403

Structure of 1068-57-1

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General Information

  • CAS No. 1068-57-1
  • Cat. No. CS-D1403
  • Purity ≥95%
  • MDL No. MFCD00007610
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₆N₂O
  • Molecular Weight 74.08
  • Synonym(s) Ethanehydrazonic acid; Hydrazine, acetyl-; Monoacetylhydrazine; NSC 2271; Acetylhydrazine); Acethydrazide
  • SMILES CC(NN)=O

Description

Cbz-N-amido-PEG20-acid is a PEG linker containing a Cbz-protected amino group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected by acidic conditions.

Synthesis

  • Route1

    References

    • US5620595 A1, ;
  • Route2
    • null|null
      108-24-7
    • ~99%
    • In-stock
      Acethydrazide|CS-D1403
      1068-57-1

    References

    • Paul, Satya; Nanda, Puja; Gupta, Rajive; Loupy, Andre Tetrahedron Letters, 2002 , vol. 43, # 23 p. 4261 - 4265
  • Route3
    • null|null
      90271-04-8
    • ~%
    • In-stock
      Acethydrazide|CS-D1403
      1068-57-1

    References

    • Ankersen, Michael; Kramer Nielsen, Karin; Kruse Hansen, Thomas; Raun, Kirsten; Sehested Hansen, Birgit European Journal of Medicinal Chemistry, 2000 , vol. 35, # 5 p. 487 - 497

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H341-H351
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   -1.0038
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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