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CS-W001157 4
Total: USD 88.00

6-Bromo-4-methylpyridine-3-carboxylic acid

  • CAS No. 1060804-74-1

  • Cat. No. CS-0194444
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromo-4-methylpyridine-3-carboxylic acid|CS-0194444

Structure of 1060804-74-1

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General Information

  • CAS No. 1060804-74-1
  • Cat. No. CS-0194444
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO₂
  • Molecular Weight 216.03
  • Synonym(s) 6-Bromo-4-methylnicotinic acid
  • SMILES CC1=CC(=NC=C1C(=O)O)Br

Description

6-Bromo-4-methylpyridine-3-carboxylic acid features a pyridine core functionalized with bromo, methyl, and carboxylic acid groups at strategic positions. This combination enables direct incorporation into cross-coupling reactions and facilitates downstream derivatization in medicinal chemistry. The molecule exhibits enhanced solubility and stability under standard conditions, making it well-suited for modular synthesis workflows.

Application

6-Bromo-4-methylpyridine-3-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-brominated pyridine core enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid and methyl groups offer orthogonal functionalization potential. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.85072
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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