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Structure of 1060804-39-8
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3-Fluoro-5-nitropyridine features a fluorine atom at the 3-position and a nitro group at the 5-position on the pyridine ring, creating a highly electron-deficient heterocycle. This combination enables selective functionalization in cross-coupling reactions and facilitates incorporation into bioactive scaffolds requiring strong dipole moments and metabolic stability.
3-Fluoro-5-nitropyridine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C3 position via nucleophilic substitution due to the activating effect of the adjacent nitro group. Its bench-stable nature and compatibility with palladium-catalyzed cross-coupling reactions facilitate efficient access to substituted pyridines and heterocyclic scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: