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Structure of 106014-25-9
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Methyl 4-fluoro-2-formylbenzoate features a fluorinated aromatic ring with strategically positioned formyl and ester groups, enabling direct incorporation into Suzuki-Miyaura coupling and Ullmann-type reactions. The electron-deficient benzene core enhances reactivity in cross-coupling processes, while the formyl moiety serves as a handle for subsequent functionalization via nucleophilic addition or condensation chemistry.
Methyl 4-fluoro-2-formylbenzoate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted benzimidazoles and other heterocyclic scaffolds. The ortho-formyl group facilitates electrophilic substitution and condensation reactions, while the fluorine substituent enhances metabolic stability and modulates electronic properties. Bench-stable and compatible with standard purification techniques, it functions effectively in multi-step syntheses requiring precise functional group placement.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: