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Structure of 1059735-34-0
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7-Benzyl-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine features a rigid, electron-deficient heterocyclic core paired with a benzylic handle for downstream functionalization. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibition and exhibits favorable stability under standard bench conditions.
7-Benzyl-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. The molecule features two electrophilic chlorides at C2 and C4, enabling nucleophilic substitution under mild conditions. Its benzylic group enhances solubility and stability, while the tetrahydropyridopyrimidine core provides a rigid scaffold suitable for functionalization in drug discovery workflows. Functions effectively in Pd-catalyzed cross-coupling and amine substitution reactions, offering high yields and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: