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CS-W001157 4
Total: USD 88.00

1-Isopropyl-1H-imidazol-2-amine

  • CAS No. 1056619-71-6

  • Cat. No. CS-0139788
  • Molecule weight125.17
  • Purity≥97%
  • MDL No.MFCD12403595

*For research and further manufacturing use only, not for direct human use.

1-Isopropyl-1H-imidazol-2-amine|CS-0139788

Structure of 1056619-71-6

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General Information

  • CAS No. 1056619-71-6
  • Cat. No. CS-0139788
  • Purity ≥97%
  • MDL No. MFCD12403595
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁N₃
  • Molecular Weight 125.17
  • Synonym(s) 1-propan-2-ylimidazol-2-amine
  • SMILES NC1=NC=CN1C(C)C

Description

1-Isopropyl-1H-imidazol-2-amine features a sterically hindered imidazole core with a primary amine at the 2-position, enabling robust coordination in catalytic systems. The isopropyl substituent enhances solubility in organic media while maintaining bench stability under standard conditions. This derivative serves as a modular scaffold for ligand development in transition metal catalysis and functional materials.

Application

1-Isopropyl-1H-imidazol-2-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of imidazole-based scaffolds prevalent in bioactive molecules. Its amine functionality facilitates straightforward derivatization, while the isopropyl group enhances metabolic stability and modulates lipophilicity. The compound exhibits good bench stability and compatibility with standard coupling protocols, making it well-suited for parallel synthesis campaigns and API intermediate development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   43.84
  • LogP   1.0462
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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