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CS-W001157 4
Total: USD 88.00

(2-Fluoro-6-phenoxyphenyl)boronic acid

  • CAS No. 1056372-58-7

  • Cat. No. CS-0174131
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-Fluoro-6-phenoxyphenyl)boronic acid|CS-0174131

Structure of 1056372-58-7

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General Information

  • CAS No. 1056372-58-7
  • Cat. No. CS-0174131
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₀BFO₃
  • Molecular Weight 232.02
  • Synonym(s) 2-Fluoro-6-phenoxyphenylboronic acid
  • SMILES OB(O)C1=C(F)C=CC=C1OC2=CC=CC=C2

Description

This boronic acid features a phenoxy-substituted aryl moiety with a fluorine atom at the ortho position, enhancing electronic modulation and metabolic stability. The boronic acid group enables efficient Suzuki-Miyaura coupling under standard conditions, delivering robust C–C bond formation in complex molecule synthesis. Designed for high functional group tolerance and bench-stable handling, it integrates seamlessly into medicinal chemistry and materials development workflows.

Application

(2-Fluoro-6-phenoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. Its stability under ambient conditions and tolerance to diverse functional groups facilitate straightforward synthesis of fluorinated aromatic scaffolds relevant to medicinal chemistry and agrochemical development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   1.2978
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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