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Structure of 105252-99-1
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4-Amino-6-fluoro-1H-pyridin-2-one features a strategically positioned amino group and fluorine atom on a pyridinone scaffold, enabling enhanced electronic modulation and metabolic stability. This electron-deficient heterocycle integrates readily into bioactive molecules, offering improved solubility and binding affinity in medicinal chemistry applications.
4-Amino-6-fluoro-1H-pyridin-2-one serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated pyridinone scaffolds. Its amino and fluoro substituents provide orthogonal reactivity for downstream functionalization, while the pyridinone core offers enhanced solubility and hydrogen-bonding capacity. The compound exhibits good bench stability and compatibility with standard coupling and cross-coupling protocols, facilitating rapid diversification in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: