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Structure of 105174-97-8
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Ethyl 3-bromoisoxazole-5-carboxylate features a brominated isoxazole core enabling direct functionalization in late-stage diversification. The ethyl ester group facilitates smooth hydrolysis and coupling reactions, while the electron-deficient heterocycle enhances reactivity in transition-metal-catalyzed transformations. This bench-stable reagent integrates readily into synthetic sequences requiring halogen-directed C–H activation or cross-coupling protocols.
Ethyl 3-bromoisoxazole-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the C3 position via palladium-catalyzed cross-coupling reactions. Its bromine substituent offers high reactivity and compatibility with standard coupling protocols, while the isoxazole core provides robust stability and favorable polarity for purification. This compound facilitates efficient access to substituted isoxazoles relevant to medicinal chemistry and agrochemical research.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: