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CS-W001157 4
Total: USD 88.00

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine

  • CAS No. 104322-63-6

  • Cat. No. CS-W008074
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine|CS-W008074

Structure of 104322-63-6

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General Information

  • CAS No. 104322-63-6
  • Cat. No. CS-W008074
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅NO₃S
  • Molecular Weight 229.30
  • Synonym(s) 9,9-dimethyltetrahydro-4a,7-methanooxazireno[3,2-i][2,1]benzothiazole 3,3-dioxide; (1S)-(+)-(10-Camphorsulfonyl)oxaziridine
  • SMILES CC1(C)[C@]23CS(N4[C@]2(O4)C[C@@]1([H])CC3)(=O)=O

Description

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine can be used:To convert prochiral ketone enolates into optically active -hydroxy ketones via enantioselective asymmetric oxidation.In the synthesis of thymidine oligonucleotides connected through pyrophosphates.In the asymmetric synthesis of proton pump inhibitors like (R)-Rabeprazole sodium and (R)-Lansoprazole sodium from the corresponding DBU salt of prochiral sulfide.In the preparation of phosphonoacetate and thiophosphonoacetate oligodeoxynucleotides by oxidizing the corresponding phosphinoacetate.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 110, p. 8477
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 110, p. 8477
  • Route3
    • (1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonamide|CS-W014175
      60933-63-3
    • ~%
    • In-stock
      (1S)-(+)-(10-Camphorsulfonyl)oxaziridine|CS-W008074
      104322-63-6

    References

    • Journal of the American Chemical Society, , vol. 110, p. 8477

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.68
  • LogP   1.0996
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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