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Structure of 1037175-81-7
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Methyl 5,8-dioxaspiro[3.4]octane-2-carboxylate features a rigid spirocyclic core that imparts exceptional stereochemical stability. This scaffold integrates a masked aldehyde equivalent and a reactive ester group, enabling selective transformations in complex molecule synthesis. The compound exhibits excellent bench stability and solubility in common organic solvents, facilitating its use in iterative synthetic sequences without degradation.
Methyl 5,8-dioxaspiro[3.4]octane-2-carboxylate serves as a versatile bicyclic building block for the synthesis of complex heterocyclic systems and natural product analogs. Its spirocyclic core provides rigidity and defined stereochemistry, enabling controlled functionalization at the C2 position. The ester group facilitates downstream transformations, while the oxetane ring offers enhanced metabolic stability in medicinal chemistry applications. The compound exhibits good bench stability and is compatible with standard coupling and reduction protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: