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Structure of 1036389-83-9
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2-Bromo-4-fluoro-5-nitrobenzoic acid features a highly electron-deficient aromatic core, enabling efficient coupling in cross-coupling and Ullmann-type reactions. The carboxylic acid group facilitates direct derivatization, while the bromo and fluoro substituents provide orthogonal reactivity for sequential functionalization. This compound serves as a key building block in medicinal chemistry and advanced materials synthesis.
2-Bromo-4-fluoro-5-nitrobenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct introduction of halogen, nitro, and carboxylic acid functionalities in a single aromatic scaffold. Its well-defined reactivity profile supports palladium-catalyzed cross-coupling, nucleophilic aromatic substitution, and derivatization via the carboxylic acid group. The molecule exhibits good bench stability and facilitates straightforward purification, making it suitable for multi-step synthetic sequences requiring orthogonal functional group handling.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: