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CS-W001157 4
Total: USD 88.00

5-Fluoro-2'-deoxycytidine

  • CAS No. 10356-76-0

  • Cat. No. CS-0064397
  • Purity≥97%
  • MDL No.MFCD00077348

*For research and further manufacturing use only, not for direct human use.

5-Fluoro-2'-deoxycytidine|CS-0064397

Structure of 10356-76-0

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General Information

  • CAS No. 10356-76-0
  • Cat. No. CS-0064397
  • Purity ≥97%
  • MDL No. MFCD00077348
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂FN₃O₄
  • Molecular Weight 245.21
  • Synonym(s) FdCyd; NSC-48006
  • SMILES O[C@H]1C[C@H](N2C(N=C(N)C(F)=C2)=O)O[C@@H]1CO

Description

Inhibiting DNA methyltransferase activity, 5-Fluoro-2′-deoxycytidine (CAS 10356-76-0) incorporates into nascent DNA strands to induce irreversible epigenetic silencing in proliferating cell lines.

Synthesis

  • Route1
    • null|null
      92574-68-0
    • ~67%
    • In-stock
      5-Fluoro-2'-deoxycytidine|CS-0064397
      10356-76-0

    References

    • Yamaguchi; Saneyoshi Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 4 p. 1441 - 1450
  • Route2
    • null|null
      161179-94-8
    • ~%
    • In-stock
      5-Fluoro-2'-deoxycytidine|CS-0064397
      10356-76-0

    References

    • Journal of Organic Chemistry, , vol. 57, # 11 p. 2989 - 2991
  • Route3
    • null|null
      110522-47-9
    • ~%
    • In-stock
      5-Fluoro-2'-deoxycytidine|CS-0064397
      10356-76-0

    References

    • Journal of Organic Chemistry, , vol. 57, # 11 p. 2989 - 2991

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   110.6
  • LogP   -1.3947
  • H_Acceptors   7
  • H_Donors   3
  • Rotatable_Bonds   2

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