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Structure of 1034690-61-3
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3-Iodo-4-(trifluoromethyl)benzoic acid features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the iodine substituent enables facile cross-coupling reactions. This combination delivers a robust platform for constructing complex bioactive architectures in medicinal chemistry and materials science.
3-Iodo-4-(trifluoromethyl)benzoic acid serves as a versatile building block for constructing biologically active heterocycles and pharmaceutical scaffolds. Its iodine handle enables reliable Suzuki, Stille, and Sonogashira couplings, while the trifluoromethyl group enhances metabolic stability and lipophilicity. The carboxylic acid functionality facilitates direct derivatization or salt formation, supporting purification and solubility control. This compound exhibits excellent bench stability and functional group tolerance, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: