(2,3-Dihydrobenzofuran-5-yl)methanol

Name: (2,3-Dihydrobenzofuran-5-yl)methanol
Brand: ChemScene
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CAS No. 103262-35-7
Cat. No. CS-M0931
Purity≥96%
MDL No.MFCD02169755

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(2,3-Dihydrobenzofuran-5-yl)methanol|CS-M0931

Structure of 103262-35-7

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Description

This bench-stable benzofuran scaffold integrates a reactive primary alcohol at the 5-position, enabling straightforward functionalization. The fused ring system imparts rigidity and enhanced metabolic stability, making it valuable for medicinal chemistry campaigns targeting CNS-penetrant therapeutics.

Application

(2,3-Dihydrobenzofuran-5-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its benzylic alcohol functionality facilitates straightforward derivatization via oxidation, protection, or coupling reactions. The dihydrobenzofuran core imparts metabolic stability and favorable pharmacokinetic properties, making it valuable for scaffold elaboration in API development. Bench-stable and compatible with standard synthetic protocols, it functions effectively in multi-step synthesis workflows.

General Information

CAS No. 103262-35-7
Cat. No. CS-M0931
Purity ≥96%
MDL No. MFCD02169755
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀O₂
Molecular Weight 150.17
Synonym(s) 2,3-Dihydro-1-benzofuran-5-ylmethanol
SMILES OCC1=CC=C(OCC2)C2=C1

Computational Chemistry Data

TPSA 29.46
LogP 1.1138
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Benzofuran compounds

Key Words

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(2,3-Dihydrobenzofuran-5-yl)methanol

CAS No. 103262-35-7

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