Lot numbers can be found on the outside label of a product:
4-(Benzyloxy)-4-oxobutanoic acid
-
CAS No. 103-40-2
- Cat. No. CS-W002611
- Purity≥97%
- MDL No.MFCD00447717
*For research and further manufacturing use only, not for direct human use.
Structure of 103-40-2
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 103-40-2
- Cat. No. CS-W002611
- Purity ≥97%
- MDL No. MFCD00447717
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₁H₁₂O₄
- Molecular Weight 208.21
- Synonym(s) None
- SMILES O=C(O)CCC(=O)OCC=1C=CC=CC1
Description
4-(Benzyloxy)-4-oxobutanoic acid features a benzyl ether-linked β-keto acid scaffold, enabling direct incorporation into synthetic sequences requiring stable, functionalized acyl precursors. The benzyloxy group provides orthogonal protection for hydroxyl functionalities during multistep transformations. This compound serves as a key intermediate in the synthesis of bioactive esters and lactones.
Application
4-(Benzyloxy)-4-oxobutanoic acid serves as a versatile building block for heterocyclic synthesis, particularly in the construction of γ-lactones and substituted pyrones. Its α,β-unsaturated ketone functionality enables Michael additions and aldol condensations under mild conditions. The benzyloxy group provides orthogonal protection for alcohols, facilitating sequential transformations. This compound exhibits good bench stability and is amenable to standard purification methods, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
Synthesis
-
References
-
Krishnan, K. Syam; Bengtsson, Christoffer; Good, James A. D.; Mirkhanov, Shamil; Chorell, Erik; Johansson, Lennart B.-A.; Almqvist, Fredrik Journal of Organic Chemistry, 2013 , vol. 78, # 23 p. 12207 - 12213
-
-
Route2
-
15026-16-1 - ~91%
-
In-stock
103-40-2
References
-
Yadav; Reddy, B. V. Subba; Rao, K. Sanjeeva; Harikishan Synlett, 2002 , # 5 p. 826 - 828
-
-
Route3
-
In-stock
108-30-5 -
121-44-8
- ~85%
-
In-stock
103-40-2
References
-
NeoRx Corporation Patent: US5112953 A1, 1992 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 63.6
- LogP 1.5946
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 5
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 4-(Benzyloxy)-4-oxobutanoic acid sigma4-(Benzyloxy)-4-oxobutanoic acid manufacturer4-(Benzyloxy)-4-oxobutanoic acid price4-(Benzyloxy)-4-oxobutanoic acid structure4-(Benzyloxy)-4-oxobutanoic acid SDSbuy 4-(Benzyloxy)-4-oxobutanoic acid4-(Benzyloxy)-4-oxobutanoic acid supplier4-(Benzyloxy)-4-oxobutanoic acid uses4-(Benzyloxy)-4-oxobutanoic acid molecular weightprice of 4-(Benzyloxy)-4-oxobutanoic acid4-(Benzyloxy)-4-oxobutanoic acid chemical name formula of 4-(Benzyloxy)-4-oxobutanoic acid