N,N'-Dimorpholine Disulfide

Name: N,N'-Dimorpholine Disulfide
Brand: ChemScene
Availability: InStock
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CAS No. 103-34-4
Cat. No. CS-0196466
Purity≥95%
MDL No.MFCD00023319

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 103-34-4

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Description

N,N'-Dimorpholine Disulfide serves as a stable, moisture-tolerant disulfide linker for conjugating biomolecules and functionalizing surfaces. Featuring two morpholine rings flanking a disulfide bond, it enables efficient thiol-disulfide exchange under physiological conditions. This structure delivers robust reactivity with cysteine residues while maintaining shelf stability and ease of handling in aqueous environments.

Application

N,N'-Dimorpholine Disulfide serves as a stable, bench-ready oxidizing agent for the formation of disulfide bonds in peptide and protein synthesis. It facilitates selective cysteine oxidation under mild conditions, offering excellent functional group tolerance and ease of purification. Its morpholine-based structure enhances solubility in polar solvents, enabling efficient coupling in aqueous-organic mixtures. This reagent is particularly valuable for constructing cystine bridges in complex biomolecules with high reproducibility.

General Information

CAS No. 103-34-4
Cat. No. CS-0196466
Purity ≥95%
MDL No. MFCD00023319
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₆N₂O₂S₂
Molecular Weight 236.36
Synonym(s) Rubber Accelerator DTDM
SMILES C1COCCN1SSN2CCOCC2

Computational Chemistry Data

TPSA 24.94
LogP 0.8622
H_Acceptors 6
H_Donors 0
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07,GHS09
Signal Word : Warning	UN#: 3077
Class : 9	Packing Group : Ⅲ
Hazard Statements : H317-H335-H401-H411
Precautionary Statements : P261-P271-P272-P273-P280-P302+P352-P363-P391-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Key Words

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N,N'-Dimorpholine Disulfide

CAS No. 103-34-4

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