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CS-W001157 4
Total: USD 88.00

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(4-(tert-butoxy)-4-oxobutyl)-L-cysteine

  • CAS No. 102971-73-3

  • Cat. No. CS-0100981
  • Molecule weight485.59
  • Purity≥97%
  • MDL No.MFCD11226818

*For research and further manufacturing use only, not for direct human use.

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(4-(tert-butoxy)-4-oxobutyl)-L-cysteine|CS-0100981

Structure of 102971-73-3

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General Information

  • CAS No. 102971-73-3
  • Cat. No. CS-0100981
  • Purity ≥97%
  • MDL No. MFCD11226818
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₃₁NO₆S
  • Molecular Weight 485.59
  • Synonym(s) None
  • SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CSCCCC(OC(C)(C)C)=O

Description

This fluorenylmethoxycarbonyl-protected cysteine derivative features a sterically hindered tert-butoxy-ketone side chain, enabling selective conjugation in peptide synthesis. The fluoren-9-ylmethoxycarbonyl group ensures efficient N-terminal protection, while the reactive thiol moiety facilitates site-specific bioconjugation under mild conditions.

Application

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(4-(tert-butoxy)-4-oxobutyl)-L-cysteine serves as a protected cysteine building block for peptide synthesis, enabling selective side-chain functionalization. The Fmoc group provides orthogonal protection for the amine, while the tert-butyl ester and ketone functionalities allow for subsequent derivatization via reductive amination or nucleophilic addition. Bench-stable and compatible with standard coupling protocols, it facilitates efficient incorporation into complex peptide scaffolds and heterocyclic systems.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   101.93
  • LogP   4.8334
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   10

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