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2-(((4-Methoxy-3-methylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole Rabeprazole Impurity

  • CAS No. 102804-82-0

  • Cat. No. CS-0166551
  • Purity≥98%
  • MDL No.MFCD08274753

*For research and further manufacturing use only, not for direct human use.

2-(((4-Methoxy-3-methylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole Rabeprazole Impurity|CS-0166551

Structure of 102804-82-0

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General Information

  • CAS No. 102804-82-0
  • Cat. No. CS-0166551
  • Purity ≥98%
  • MDL No. MFCD08274753
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₅N₃OS
  • Molecular Weight 285.36
  • Synonym(s) 4-Desmethoxypropoxyl-4-methoxy S-Deoxo Rabeprazole
  • SMILES CC1=C(OC)C=CN=C1CSC2=NC3=CC=CC=C3N2

Synthesis

  • Route1
    • In-stock
      (4-Methoxy-3-methylpyridin-2-yl)methyl acetate|CS-0878412
      102625-98-9
    • null|null
      134469-07-1
    • ~21%
    • In-stock
      2-(((4-Methoxy-3-methylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole Rabeprazole Impurity|CS-0166551
      102804-82-0

    References

    • Arigen, Pharmaceuticals, Inc. Patent: EP2103608 A1, 2009 ; Location in patent: Page/Page column 17 ;
  • Route2
    • In-stock
      2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride|CS-0456656
      86604-74-2
    • null|null
      134469-07-1
    • ~90%
    • In-stock
      2-(((4-Methoxy-3-methylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole Rabeprazole Impurity|CS-0166551
      102804-82-0

    References

    • Pingili, R. Reddy; Jambula, M. Reddy; Ganta, M. Reddy; Ghanta, M. Reddy; Sajja; Sundaram; Boluggdu, V. Bhaskar Pharmazie, 2005 , vol. 60, # 11 p. 814 - 818
  • Route3
    • null|null
      37699-43-7
    • ~%
    • In-stock
      2-(((4-Methoxy-3-methylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole Rabeprazole Impurity|CS-0166551
      102804-82-0

    References

    • Kuehler, Thomas C.; Swanson, Marianne; Shcherbuchin, Vladimir; Larsson, Hakan; Mellgard, Bjoern; Sjoestroem, Jan-Eric Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1777 - 1788

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.8
  • LogP   3.56722
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   4

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