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CS-W001157 4
Total: USD 88.00

Potassium trifluoro(((4-methoxybenzyl)oxy)methyl)borate

  • CAS No. 1027642-26-7

  • Cat. No. CS-0159034
  • Purity≥95%
  • MDL No.MFCD11505925

*For research and further manufacturing use only, not for direct human use.

Potassium trifluoro(((4-methoxybenzyl)oxy)methyl)borate|CS-0159034

Structure of 1027642-26-7

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General Information

  • CAS No. 1027642-26-7
  • Cat. No. CS-0159034
  • Purity ≥95%
  • MDL No. MFCD11505925
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BF₃KO₂
  • Molecular Weight 258.09
  • Synonym(s) Potassium (4-methoxy)benzyloxymethyltrifluoroborate
  • SMILES F[B-](F)(COCC1=CC=C(OC)C=C1)F.[K+]

Description

Potassium trifluoro(((4-methoxybenzyl)oxy)methyl)borate delivers a stable, moisture-tolerant boronate handle for Suzuki-Miyaura coupling. The para-methoxybenzyl protecting group ensures high solubility and compatibility with aqueous workups, enabling efficient cross-coupling under mild conditions. This reagent integrates seamlessly into complex molecule assembly workflows.

Application

Potassium trifluoro(((4-methoxybenzyl)oxy)methyl)borate serves as a stable, bench-ready boron reagent enabling efficient Suzuki-Miyaura cross-coupling reactions. Its trifluoroborate functionality provides excellent functional group tolerance and compatibility with diverse aryl, heteroaryl, and vinyl electrophiles. The 4-methoxybenzyl protecting group ensures high chemical stability during storage and handling, while allowing straightforward deprotection under mild acidic conditions. This reagent facilitates reliable C–C bond formation in complex molecule synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   -0.3976
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   5

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