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Structure of 102735-84-2
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5-Chloro-1H-indazole-3-carbaldehyde delivers a potent electron-deficient heterocyclic scaffold featuring a reactive aldehyde group at the 3-position. This configuration enables direct coupling in amide bond formation and facilitates integration into bioactive molecules. The chloro substituent enhances metabolic stability and modulates electronic properties, making it valuable for medicinal chemistry and targeted synthesis.
5-Chloro-1H-indazole-3-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to indazole-based scaffolds in medicinal chemistry. The aldehyde functionality facilitates reductive amination, Wittig reactions, and coupling with nucleophiles, while the chloro substituent supports further functionalization via palladium-catalyzed cross-coupling. Bench-stable and readily purified by recrystallization, it functions effectively in standard synthetic workflows requiring orthogonality and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: