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Structure of 10252-82-1
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4-(Morpholine-4-sulfonyl)benzoic acid features a morpholine sulfonamide moiety linked to a benzoic acid core, delivering enhanced solubility and metabolic stability. This combination enables efficient integration into bioactive scaffolds for medicinal chemistry campaigns. The electron-deficient aryl ring facilitates electrophilic coupling reactions under standard conditions.
4-(Morpholine-4-sulfonyl)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through standard amide coupling and Suzuki-Miyaura cross-coupling reactions. The morpholine-sulfonyl group enhances solubility and modulates electronic properties, while the carboxylic acid functionality provides reliable conjugation points for peptide and heterocyclic extensions. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for iterative synthesis workflows in drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: