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Structure of 1024583-33-2
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This methyl ester derivative integrates a brominated benzothiazole core with a carboxylic acid ester functionality, enabling direct use in cross-coupling reactions. The electron-deficient heterocycle and reactive ester group facilitate efficient C–C bond formation under palladium catalysis, offering a stable, bench-ready platform for synthesizing complex biaryl architectures.
2-Bromobenzothiazole-6-carboxylic acid methyl ester serves as a versatile building block for the synthesis of bioactive heterocycles, enabling palladium-catalyzed cross-coupling reactions and functionalization at the carboxylate position. Its bromo substituent facilitates C–C bond formation under standard Suzuki or Stille conditions, while the methyl ester group offers straightforward hydrolysis to the corresponding carboxylic acid. The molecule exhibits good bench stability and compatibility with common protecting group strategies, making it suitable for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: