6-Methyl-5-(trifluoromethyl)pyridin-2-amine

Name: 6-Methyl-5-(trifluoromethyl)pyridin-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1023813-33-3
Cat. No. CS-0439934
Purity≥96%
MDL No.MFCD09881222

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Methyl-5-(trifluoromethyl)pyridin-2-amine|CS-0439934

Structure of 1023813-33-3

Size

Price

Quantity

* Please select Quantity before adding items.

Description

6-Methyl-5-(trifluoromethyl)pyridin-2-amine features a trifluoromethyl group that imparts enhanced electron-withdrawal and metabolic stability, while the methyl substituent fine-tunes electronic properties. This pyridine scaffold serves as a key building block in medicinal chemistry, particularly for kinase inhibitors and bioactive heterocycles.

Application

6-Methyl-5-(trifluoromethyl)pyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling and electrophilic substitution reactions. Its electron-deficient pyridine core exhibits favorable reactivity in C–H functionalization and Suzuki-Miyaura coupling, while the methyl and trifluoromethyl groups provide steric and electronic modulation. The compound demonstrates bench stability and compatibility with standard purification protocols, facilitating integration into multi-step synthetic sequences for drug discovery applications.

General Information

CAS No. 1023813-33-3
Cat. No. CS-0439934
Purity ≥96%
MDL No. MFCD09881222
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₇F₃N₂
Molecular Weight 176.14
Synonym(s) 6-Methyl-5-trifluoromethyl-pyridin-2-ylamine
SMILES CC1=NC(=CC=C1C(F)(F)F)N

Computational Chemistry Data

TPSA 38.91
LogP 1.99102
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

1023813-33-3 sigma1023813-33-3 manufacturer1023813-33-3 price1023813-33-3 structure1023813-33-3 SDSbuy 1023813-33-31023813-33-3 supplier1023813-33-3 uses1023813-33-3 molecular weightprice of 1023813-33-31023813-33-3 chemical name formula of 1023813-33-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Methyl-5-(trifluoromethyl)pyridin-2-amine

CAS No. 1023813-33-3

Recommended Products