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CS-W001157 4
Total: USD 88.00

4-Fluoro-4-methylpiperidine hydrochloride

  • CAS No. 1023305-87-4

  • Cat. No. CS-0187010
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Fluoro-4-methylpiperidine hydrochloride|CS-0187010

Structure of 1023305-87-4

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General Information

  • CAS No. 1023305-87-4
  • Cat. No. CS-0187010
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃ClFN
  • Molecular Weight 153.63
  • Synonym(s) 1,3-Dioxolan-2-one,4-fluoro-4-methyl
  • SMILES CC1(CCNCC1)F.Cl

Description

4-Fluoro-4-methylpiperidine hydrochloride is a bench-stable, moisture-tolerant heterocyclic amine featuring a fluorinated methylpiperidine core. This derivative integrates a strategically positioned fluorine atom and a tertiary nitrogen, enabling efficient coupling in medicinal chemistry workflows. The hydrochloride salt enhances solubility and handling, streamlining use in synthesis and formulation applications.

Application

4-Fluoro-4-methylpiperidine hydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated piperidine scaffolds prevalent in bioactive molecules. Its tertiary amine functionality offers enhanced metabolic stability and improved membrane permeability. The compound exhibits excellent bench stability, facilitates straightforward salt formation, and demonstrates broad compatibility with standard coupling and functionalization protocols in API synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.5198
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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