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Structure of 101987-86-4
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Ethyl 3-(3-chloro-2,4,5-trifluorophenyl)-3-oxopropanoate features a trifluorinated aryl core with strategic chlorine and carbonyl functionalities, enabling direct integration into cascade cyclizations. The electron-deficient enone system facilitates nucleophilic attack under mild conditions, while the ethyl ester group supports downstream derivatization. This bench-stable reagent streamlines access to complex fluorinated heterocycles in medicinal chemistry.
Ethyl 3-(3-chloro-2,4,5-trifluorophenyl)-3-oxopropanoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to fluorinated heterocycles and pharmaceutical intermediates. The α,β-unsaturated ester moiety facilitates Michael additions, condensations, and cyclizations under mild conditions. Bench-stable and readily purified by distillation or chromatography, it exhibits excellent functional group tolerance and compatibility with standard coupling protocols, making it ideal for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: