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CS-W001157 4
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3-Cyclopropylprop-2-yn-1-ol

  • CAS No. 101974-69-0

  • Cat. No. CS-0051385
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Cyclopropylprop-2-yn-1-ol|CS-0051385

Structure of 101974-69-0

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General Information

  • CAS No. 101974-69-0
  • Cat. No. CS-0051385
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈O
  • Molecular Weight 96.13
  • Synonym(s) 3-Cyclopropylprop-2-on-1-Ol
  • SMILES OCC#CC1CC1

Description

3-Cyclopropylprop-2-yn-1-ol features a terminal alkyne group flanked by a cyclopropyl moiety and a primary hydroxyl, enabling efficient copper-catalyzed coupling reactions. This scaffold combines structural rigidity from the strained cyclopropane ring with high reactivity in click chemistry applications.

Application

3-Cyclopropylprop-2-yn-1-ol serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized alkynes and heterocyclic scaffolds. Its terminal alkyne functionality facilitates reliable copper-catalyzed coupling reactions, while the hydroxyl group supports orthogonal transformations. The cyclopropyl moiety imparts structural rigidity and enhanced metabolic stability, making this compound valuable for medicinal chemistry applications requiring defined stereochemical control and favorable physicochemical properties.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1987
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   0.3921
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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