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Structure of 1019023-12-1
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6-Bromo-[1,2,4]triazolo[4,3-a]pyrimidine is a heterocyclic building block featuring a bromine substituent at the 6-position of a fused triazolopyrimidine core. This electron-deficient scaffold enables direct functionalization in palladium-catalyzed cross-coupling reactions, offering efficient access to bioactive derivatives. The molecule exhibits excellent stability under standard reaction conditions and integrates readily into complex molecular architectures.
6-Bromo-[1,2,4]triazolo[4,3-a]pyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via Pd-catalyzed cross-coupling reactions. The bromine substituent facilitates reliable C–C and C–heteroatom bond formation under standard conditions, while the fused triazolopyrimidine core offers enhanced metabolic stability and predictable binding interactions. Its bench-stable, crystalline nature supports straightforward handling and purification, making it well-suited for modular synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: