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Structure of 1016258-69-7
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1-tert-Butyl 4-ethyl 4-(aminomethyl)piperidine-1,4-dicarboxylate is a bench-stable piperidine derivative featuring orthogonal functional handles: a protected amine and an ester group. This scaffold integrates seamlessly into late-stage diversification strategies, enabling direct coupling with electrophiles or selective deprotection under mild conditions. The tert-butyl and ethyl esters provide enhanced solubility and stability during synthetic manipulations.
1-tert-Butyl 4-ethyl 4-(aminomethyl)piperidine-1,4-dicarboxylate serves as a versatile bis-protected piperidine building block, enabling efficient access to complex nitrogen-containing scaffolds. The tert-butyl and ethyl ester groups provide orthogonal protection for amine and carboxylic acid functionalities, facilitating sequential deprotection and functionalization. Its aminomethyl side chain offers a direct handle for further derivatization via alkylation, acylation, or coupling reactions, making it particularly valuable in medicinal chemistry campaigns requiring modular heterocyclic synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: