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CS-W001157 4
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(4,5-Dimethoxy-2-nitrophenyl)methanol

  • CAS No. 1016-58-6

  • Cat. No. CS-0104904
  • Purity≥95%
  • MDL No.MFCD00014701

*For research and further manufacturing use only, not for direct human use.

(4,5-Dimethoxy-2-nitrophenyl)methanol|CS-0104904

Structure of 1016-58-6

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General Information

  • CAS No. 1016-58-6
  • Cat. No. CS-0104904
  • Purity ≥95%
  • MDL No. MFCD00014701
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₅
  • Molecular Weight 213.19
  • Synonym(s) 6-Nitroveratryl Alcohol
  • SMILES OCC1=CC(OC)=C(OC)C=C1[N+]([O-])=O

Description

4,5-Dimethoxy-2-nitrobenzyl alcohol (6-Nitroveratryl Alcohol) is 2-nitrobenzyl alcohol derivative. It has been reported to be one of the oxidation products of veratryl (3,4-dimethoxybenzyl) alcohol by lignin peroxidase (isolated from Phanerochaete chrysosporium).4,5-Dimethoxy-2-nitrobenzyl alcohol (6-nitroveratryl alcohol) is suitable reagent used in the synthesis of 4,5-dimethoxy-2-nitrobenzyl methacrylate, a photolabile monomer and 2-(4-((4-(4,5-dimethoxy-2-nitrobenzyloxy)phenyl)cyclohexylidene)methyl)phenoxy)-N,N-dimethylethanamine, a caged cyclofen-OH ligand.It may be used in the synthesis of the following:1-[[(chlorocarbonyl)oxy]methyl]-4,5-dimethoxy-2-nitrobenzenebis(4,5-dimethoxy-2-nitrophenyl)ethylene glycol, a photolabile protecting groupoptically-sensitive monomernitroveratryl (NV) protected -hydroxyacetic acid (G) (NV-G-OH), required in the preparation of nitroveratryl (NV) protected cyanomethyl (CM) ester of -hydroxyacetic acid (G) (NV-G-CM)4,5-dimethoxy-2-nitrobenzyl p-nitro-phenylcarbonate6-nitroveratryloxycarbonyl chloride (NVOCCl), a reagent used in the protection of amino function in amino sugars

Synthesis

  • Route1

    References

    • Reinhard, Robert; Schmidt, Brigitte F. Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2434 - 2441
  • Route2
    • null|null
      165811-64-3
    • ~%
    • In-stock
      (4,5-Dimethoxy-2-nitrophenyl)methanol|CS-0104904
      1016-58-6

    References

    • Chemical Communications, , vol. 48, # 5 p. 657 - 659
  • Route3
    • null|null
      1236141-68-6
    • ~%
    • In-stock
      (4,5-Dimethoxy-2-nitrophenyl)methanol|CS-0104904
      1016-58-6

    References

    • Macromolecules, , vol. 44, # 21 p. 8590 - 8597

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   81.83
  • LogP   1.1043
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   4

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