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CS-W001157 4
Total: USD 88.00

(((5-Bromopentyl)oxy)methyl)benzene

  • CAS No. 1014-93-3

  • Cat. No. CS-0132768
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(((5-Bromopentyl)oxy)methyl)benzene|CS-0132768

Structure of 1014-93-3

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General Information

  • CAS No. 1014-93-3
  • Cat. No. CS-0132768
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇BrO
  • Molecular Weight 257.17
  • Synonym(s) Benzyloxypentyl Bromide
  • SMILES BrCCCCCOCC1=CC=CC=C1

Description

This benzyl ether features a brominated aliphatic chain enabling facile functionalization. The (5-bromopentyl)oxy group provides a reactive handle for nucleophilic substitution, facilitating conjugation with biomolecules or polymer backbones under mild conditions. The aromatic core enhances stability and solubility in organic media.

Application

((5-Bromopentyl)oxy)methyl)benzene serves as a versatile bifunctional building block, enabling efficient tethering of aromatic moieties to aliphatic chains via its pendant bromide and ether functionalities. The bromide facilitates nucleophilic substitution in Pd-catalyzed coupling reactions, while the benzylic ether offers stability and compatibility with standard synthetic workflows. This structure functions effectively in the construction of complex molecular architectures, including macrocyclic systems and functionalized polymers, with predictable reactivity and straightforward purification.

Synthesis

  • Route1

    References

    • Nature Chemistry, , vol. 3, # 2 p. 140 - 145
  • Route2
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      558-13-4
    • In-stock
      5-(Benzyloxy)pentan-1-ol|CS-W010646
      4541-15-5
    • ~%
    • In-stock
      (((5-Bromopentyl)oxy)methyl)benzene|CS-0132768
      1014-93-3

    References

    • US2003/69434 A1, ;
  • Route3
    • null|null
      821-25-0
    • null|null
      558-13-4
    • In-stock
      5-(Benzyloxy)pentan-1-ol|CS-W010646
      4541-15-5
    • ~%
    • In-stock
      (((5-Bromopentyl)oxy)methyl)benzene|CS-0132768
      1014-93-3

    References

    • US6677324 B1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   3.7684
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   7

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