Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-(4-Methoxyphenyl)-1,3,4-thiadiazol-2-amine

  • CAS No. 1014-25-1

  • Cat. No. CS-0063898
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-(4-Methoxyphenyl)-1,3,4-thiadiazol-2-amine|CS-0063898

Structure of 1014-25-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1014-25-1
  • Cat. No. CS-0063898
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉N₃OS
  • Molecular Weight 207.25
  • Synonym(s) 5-(4-METHOXY-PHENYL)-[1,3,4]THIADIAZOL-2-YLAMINE
  • SMILES NC1=NN=C(C2=CC=C(OC)C=C2)S1

Description

5-(4-Methoxyphenyl)-1,3,4-thiadiazol-2-amine features a conjugated thiadiazole core linked to a para-methoxyphenyl group, delivering enhanced electron density and solubility. This scaffold integrates readily into bioactive molecules, enabling efficient access to pharmacologically relevant heterocycles under standard conditions.

Application

5-(4-Methoxyphenyl)-1,3,4-thiadiazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive compounds through established coupling and functionalization protocols. Its robust thiadiazole core offers favorable bench stability and compatibility with diverse reaction conditions. The methoxyphenyl substituent enhances solubility and provides a handle for further derivatization, making it a practical scaffold for targeted molecular design.

Synthesis

  • Route1

    References

    • Bioorganic and Medicinal Chemistry, , vol. 16, # 14 p. 6663 - 6668
  • Route2
    • N'-(4-methoxybenzylidene)carbamohydrazonothioic acid|CS-0320066
      4334-74-1
    • ~85%
    • In-stock
      5-(4-Methoxyphenyl)-1,3,4-thiadiazol-2-amine|CS-0063898
      1014-25-1

    References

    • Monatshefte fur Chemie, , vol. 144, # 5 p. 681 - 686
  • Route3
    • 2-(4-Methoxybenzoyl)hydrazine-1-carbothioamide|CS-0343735
      833-84-1
    • ~62%
    • In-stock
      5-(4-Methoxyphenyl)-1,3,4-thiadiazol-2-amine|CS-0063898
      1014-25-1

    References

    • Asian Journal of Chemistry, , vol. 23, # 3 p. 1305 - 1308

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   61.03
  • LogP   1.7959
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1014-25-1 sigma1014-25-1 manufacturer1014-25-1 price1014-25-1 structure1014-25-1 SDSbuy 1014-25-11014-25-1 supplier1014-25-1 uses1014-25-1 molecular weightprice of 1014-25-11014-25-1 chemical name formula of 1014-25-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label