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Structure of 10135-00-9
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3-Bromobenzo[b]thiophene-2-carbaldehyde features a brominated benzo[b]thiophene core with an aldehyde group at the 2-position, enabling direct functionalization in cross-coupling and multistep synthesis. The electron-deficient thiophene ring enhances reactivity in transition-metal catalyzed transformations. This bench-stable compound serves as a key scaffold for heterocyclic building blocks in medicinal chemistry and materials science.
3-Bromobenzo[b]thiophene-2-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal reactivity profile. The aldehyde functionality facilitates efficient derivatization via oxidation, reduction, or nucleophilic addition, while the bromine atom supports further functionalization through standard Suzuki, Stille, or Negishi coupling protocols. Bench-stable and readily purified by flash chromatography, it functions effectively in medicinal chemistry campaigns requiring fused thiophene scaffolds with tunable substitution patterns.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H319
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Precautionary Statements : P264-P270-P280-P330-P405-P501
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Lot numbers can be found on the outside label of a product: