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Structure of 1012880-11-3
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This boronate-functional aniline features a fluorinated aryl group and a methyl substituent, enabling efficient coupling in Suzuki-Miyaura reactions. The tetramethyl-dioxaborolane moiety provides enhanced stability and reactivity under standard conditions, facilitating rapid cross-coupling with aryl halides.
2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The ortho-fluoro and meta-methyl substituents enable directed functionalization and enhance metabolic stability in bioactive scaffolds. The pinacol boronate group offers excellent bench stability, tolerance to diverse reaction conditions, and facilitates straightforward purification—making this compound ideal for rapid library synthesis and late-stage diversification in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: