2-Chloro-5-methoxy-4-nitrophenol

Name: 2-Chloro-5-methoxy-4-nitrophenol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 100959-51-1
Cat. No. CS-0179639
Purity≥97%
MDL No.MFCD18431954

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-5-methoxy-4-nitrophenol|CS-0179639

Structure of 100959-51-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 100959-51-1
Cat. No. CS-0179639
Purity ≥97%
MDL No. MFCD18431954
Storage RT, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆ClNO₄
Molecular Weight 203.58
Synonym(s) 2-chloro-5-methoxy-4-nitro-phenol
SMILES OC1=CC(OC)=C([N+]([O-])=O)C=C1Cl

Description

2-Chloro-5-methoxy-4-nitrophenol features a nitro group at the para position relative to the hydroxyl, enhancing electrophilic reactivity. The chloro and methoxy substituents provide orthogonal functional handles for downstream derivatization. This electron-deficient phenolic scaffold enables efficient coupling in cross-coupling and condensation reactions under mild conditions.

Application

2-Chloro-5-methoxy-4-nitrophenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of heterocyclic scaffolds via nucleophilic aromatic substitution. Its ortho-chloro and para-nitro groups provide complementary reactivity for sequential functionalization, while the phenolic hydroxyl and methoxy substituents offer handle points for derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for multi-step synthetic sequences in industrial R&D workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07,GHS09
Signal Word : Danger	UN#: 3077
Class : 9	Packing Group : Ⅲ
Hazard Statements : H302-H315-H317-H318-H410
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 72.6
LogP 1.9624
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Chloro-5-methoxy-4-nitrophenol sigma2-Chloro-5-methoxy-4-nitrophenol manufacturer2-Chloro-5-methoxy-4-nitrophenol price2-Chloro-5-methoxy-4-nitrophenol structure2-Chloro-5-methoxy-4-nitrophenol SDSbuy 2-Chloro-5-methoxy-4-nitrophenol2-Chloro-5-methoxy-4-nitrophenol supplier2-Chloro-5-methoxy-4-nitrophenol uses2-Chloro-5-methoxy-4-nitrophenol molecular weightprice of 2-Chloro-5-methoxy-4-nitrophenol2-Chloro-5-methoxy-4-nitrophenol chemical name formula of 2-Chloro-5-methoxy-4-nitrophenol

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-5-methoxy-4-nitrophenol

CAS No. 100959-51-1

Recommended Products