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CS-W001157 4
Total: USD 88.00

Benzyl (R)-3-hydroxypyrrolidine-1-carboxylate

  • CAS No. 100858-33-1

  • Cat. No. CS-W003377
  • Purity≥98%
  • MDL No.MFCD07368258

*For research and further manufacturing use only, not for direct human use.

Benzyl (R)-3-hydroxypyrrolidine-1-carboxylate|CS-W003377

Structure of 100858-33-1

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General Information

  • CAS No. 100858-33-1
  • Cat. No. CS-W003377
  • Purity ≥98%
  • MDL No. MFCD07368258
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅NO₃
  • Molecular Weight 221.25
  • Synonym(s) benzyl (3R)-3-hydroxypyrrolidine-1-carboxylate
  • SMILES O[C@@H]1CCN(C1)C(=O)OCc1ccccc1

Synthesis

  • Route1
    • In-stock
      Pyrrolidin-3-ol|CS-W022946
      40499-83-0
    • null|null
      501-53-1
    • ~10%
    • In-stock
      Benzyl (R)-3-hydroxypyrrolidine-1-carboxylate|CS-W003377
      100858-33-1

    References

    • FOB SYNTHESIS; CHOI, Woo-Baeg; KIM, Deog-Il; GRUSZECKA-KOWALIK, Ewa; JOO, Hyung-Yeul; LIU, Shuangpei; MAO, Shuli; LI, Yongfeng Patent: WO2011/160020 A2, 2011 ; Location in patent: Page/Page column 57 ;
  • Route2
    • In-stock
      (R)-3-Pyrrolidinol hydrochloride|CS-B1358
      104706-47-0
    • null|null
      501-53-1
    • ~93%
    • In-stock
      Benzyl (R)-3-hydroxypyrrolidine-1-carboxylate|CS-W003377
      100858-33-1

    References

    • Sanchez; Domagala; Heifetz; Priebe; Sesnie; Trehan Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1764 - 1773
  • Route3

    References

    • Li; Feiten; Chang; Duetz; Van Beilen; Witholt Journal of Organic Chemistry, 2001 , vol. 66, # 25 p. 8424 - 8430

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.77
  • LogP   1.3898
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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