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CS-W001157 4
Total: USD 88.00

3-Methoxypyridine-4-boronic acid

  • CAS No. 1008506-24-8

  • Cat. No. CS-W005230
  • Purity≥95%
  • MDL No.MFCD06801698

*For research and further manufacturing use only, not for direct human use.

3-Methoxypyridine-4-boronic acid|CS-W005230

Structure of 1008506-24-8

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General Information

  • CAS No. 1008506-24-8
  • Cat. No. CS-W005230
  • Purity ≥95%
  • MDL No. MFCD06801698
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈BNO₃
  • Molecular Weight 152.94
  • Synonym(s) None
  • SMILES COC1=C(C=CN=C1)B(O)O

Description

3-Methoxypyridine-4-boronic acid features a pyridine core with strategically positioned methoxy and boronic acid groups, enabling direct incorporation into Suzuki-Miyaura cross-coupling reactions. The electron-rich aromatic system enhances reactivity while maintaining bench-stable handling characteristics under standard conditions.

Application

3-Methoxypyridine-4-boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The pyridine scaffold provides strong coordination to transition metals, while the methoxy group enhances solubility and modulates electronic properties. Bench-stable and readily purified by recrystallization, it functions reliably in the synthesis of biologically relevant heterocycles and functionalized arylated scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   62.58
  • LogP   -1.23
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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