Lot numbers can be found on the outside label of a product:
(RS)-CPP
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CAS No. 100828-16-8
- Cat. No. CS-0020444
- Purity≥98%
- MDL No.MFCD00055136
*For research and further manufacturing use only, not for direct human use.
Structure of 100828-16-8
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General Information
- CAS No. 100828-16-8
- Cat. No. CS-0020444
- Purity ≥98%
- MDL No. MFCD00055136
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₁₇N₂O₅P
- Molecular Weight 252.20
- Synonym(s) (±)-CPP
- SMILES O=C(C1NCCN(CCCP(O)(O)=O)C1)O
Description
Blocking NMDA receptor ion channels, (±)-CPP (CAS 100828-16-8) disrupts glutamatergic neurotransmission and induces neurochemical inhibition in excitatory synaptic pathways.
Application
(±)-CPP (CAS 100828-16-8) acts as an uncompetitive NMDA receptor antagonist to probe neurochemical dynamics in vivo and in vitro, enabling precise dissection of glutamatergic signaling pathways. It modulates synaptic transmission in mouse brain slices. Researchers use it to track blood glucose fluctuations and isolate hippocampal neuron activity with high fidelity.
Synthesis
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Route1
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146398-95-0 - ~76%
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In-stock
100828-16-8
References
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Demaine; Smith Synthesis, 1992 , # 11 p. 1065 - 1067
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Route2
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In-stock
2762-32-5 -
1475-93-0
- ~%
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In-stock
100828-16-8
References
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British Technology Group Limited Patent: US5399693 A1, 1995 ;
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Route3
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146398-93-8
- ~%
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In-stock
100828-16-8
References
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Demaine; Smith Synthesis, 1992 , # 11 p. 1065 - 1067
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 110.1
- LogP -1.0874
- H_Acceptors 4
- H_Donors 4
- Rotatable_Bonds 5
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Key Words
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