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CS-W001157 4
Total: USD 88.00

7-Chloro-1H-indole-3-carbaldehyde

  • CAS No. 1008-07-7

  • Cat. No. CS-W006403
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Chloro-1H-indole-3-carbaldehyde|CS-W006403

Structure of 1008-07-7

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General Information

  • CAS No. 1008-07-7
  • Cat. No. CS-W006403
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆ClNO
  • Molecular Weight 179.60
  • Synonym(s) Indole-3-carboxaldehyde,7-chloro-
  • SMILES ClC1=CC=CC2=C1NC=C2C=O

Application

7-Chloro-1H-indole-3-carbaldehyde serves as a versatile building block for the synthesis of biologically active indole derivatives. The aldehyde functionality enables efficient coupling reactions, including reductive amination and Wittig transformations, while the 7-chloro substituent provides enhanced electrophilicity and compatibility with diverse reaction conditions. Its bench-stable nature and ease of purification facilitate integration into standard medicinal chemistry workflows.

Synthesis

  • Route1

    References

    • Brigham and Women's Hospital, Inc.; President and Fellows of Harvard College Patent: US2005/119260 A1, 2005 ; Location in patent: Page/Page column 36 ;
  • Route2
    • In-stock
      Indole, 7-chloro-|CS-W020039
      53924-05-3
    • null|null
      68-12-2
    • ~%
    • In-stock
      7-Chloro-1H-indole-3-carbaldehyde|CS-W006403
      1008-07-7

    References

    • WO2007/75772 A2, ; Page/Page column 124 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   32.86
  • LogP   2.6338
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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