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CS-W001157 4
Total: USD 88.00

7-Fluoro-2H-benzo[b][1,4]thiazin-3(4H)-one

  • CAS No. 100638-20-8

  • Cat. No. CS-0473881
  • Molecule weight183.20
  • Purity≥98%
  • MDL No.MFCD12196317

*For research and further manufacturing use only, not for direct human use.

7-Fluoro-2H-benzo[b][1,4]thiazin-3(4H)-one|CS-0473881

Structure of 100638-20-8

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General Information

  • CAS No. 100638-20-8
  • Cat. No. CS-0473881
  • Purity ≥98%
  • MDL No. MFCD12196317
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆FNOS
  • Molecular Weight 183.20
  • Synonym(s) 2H-1,4-Benzothiazin-3(4H)-one, 7-fluoro-
  • SMILES O=C1NC2=C(SC1)C=C(F)C=C2

Synthesis

  • Route1
    • null|null
      96-32-2
    • 2-Amino-5-fluorobenzenethiol|CS-0662876
      33264-82-3
    • ~%
    • 7-Fluoro-2H-benzo[b][1,4]thiazin-3(4H)-one|CS-0473881
      100638-20-8

    References

    • GLAXO GROUP LIMITED; BERTANI, Barbara; CREMONESI, Susanna; GARZYA, Vincenzo; MICHELI, Fabrizio; RUPCIC, Renata; SABBATINI, Fabio Maria Patent: WO2011/151361 A1, 2011 ; Location in patent: Page/Page column 54-55 ; WO 2011/151361 A1
  • Route2
    • null|null
      105-39-5
    • null|null
      73011-24-2
    • ~62%
    • 7-Fluoro-2H-benzo[b][1,4]thiazin-3(4H)-one|CS-0473881
      100638-20-8

    References

    • Sawhney, S N; Sharma, P. K.; Bajaj, K; Gupta, A Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, p. 280 - 284
  • Route3
    • null|null
      371-40-4
    • ~%
    • 7-Fluoro-2H-benzo[b][1,4]thiazin-3(4H)-one|CS-0473881
      100638-20-8

    References

    • GLAXO GROUP LIMITED; BERTANI, Barbara; CREMONESI, Susanna; GARZYA, Vincenzo; MICHELI, Fabrizio; RUPCIC, Renata; SABBATINI, Fabio Maria Patent: WO2011/151361 A1, 2011 ; WO 2011/151361 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   1.8699
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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