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CS-W001157 4
Total: USD 88.00

2-[4-(methoxycarbonyl)-1h-pyrazol-1-yl]acetic acid

  • CAS No. 1006348-69-1

  • Cat. No. CS-0264399
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-[4-(methoxycarbonyl)-1h-pyrazol-1-yl]acetic acid|CS-0264399

Structure of 1006348-69-1

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General Information

  • CAS No. 1006348-69-1
  • Cat. No. CS-0264399
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₄
  • Molecular Weight 184.15
  • Synonym(s) [4-(methoxycarbonyl)-1H-pyrazol-1-yl]acetic acid
  • SMILES COC(=O)C1=CN(CC(=O)O)N=C1

Description

This pyrazole-acetic acid derivative integrates a methoxycarbonyl group at the 4-position of the pyrazole ring, delivering enhanced solubility and stability under standard conditions. The conjugated carboxylic acid functionality enables direct coupling in peptide synthesis or as a building block for bioconjugates.

Application

2-[4-(Methoxycarbonyl)-1H-pyrazol-1-yl]acetic acid serves as a versatile building block for constructing bioactive heterocyclic scaffolds, enabling efficient conjugation via ester hydrolysis or amide coupling. Its pyrazole core exhibits favorable stability and functional group tolerance, facilitating downstream modifications in medicinal chemistry campaigns. The molecule functions as a key intermediate in the synthesis of potential kinase inhibitors and other pharmaceutical agents, offering reliable reactivity under standard peptide coupling conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   81.42
  • LogP   -0.2457
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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