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CS-W001157 4
Total: USD 88.00

2'-Bromo-5'-fluoroacetophenone

  • CAS No. 1006-33-3

  • Cat. No. CS-0019646
  • Purity≥98%
  • MDL No.MFCD07780635

*For research and further manufacturing use only, not for direct human use.

2'-Bromo-5'-fluoroacetophenone|CS-0019646

Structure of 1006-33-3

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General Information

  • CAS No. 1006-33-3
  • Cat. No. CS-0019646
  • Purity ≥98%
  • MDL No. MFCD07780635
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrFO
  • Molecular Weight 217.04
  • Synonym(s) None
  • SMILES CC(C1=CC(F)=CC=C1Br)=O

Synthesis

  • Route1
    • 1-(2-Bromo-5-fluorophenyl)ethan-1-ol|CS-0378142
      906673-56-1
    • ~94%
    • In-stock
      2'-Bromo-5'-fluoroacetophenone|CS-0019646
      1006-33-3

    References

    • ELAN PHARMACEUTICALS, INC.; DAPPEN, Michael S.; JAGODZINSKI, Jacek J.; LATIMER, Lee H.; WU, Jing; GODFREY, Jollie Duaine, Jr.; MATUNAS, Robert M.; DRABB, Thomas W. Patent: WO2010/111418 A2, 2010 ; Location in patent: Page/Page column 99 ;
  • Route2
    • null|null
      75-16-1
    • In-stock
      2-Bromo-5-fluorobenzonitrile|CS-W008055
      57381-39-2
    • ~44%
    • In-stock
      2'-Bromo-5'-fluoroacetophenone|CS-0019646
      1006-33-3

    References

    • TIBOTEC PHARMACEUTICALS; VENDEVILLE, Sandrine, Marie, Helene; RABOISSON, Pierre, Jean-Marie, Bernard; LIN, Tse-I Patent: WO2010/3658 A1, 2010 ; Location in patent: Page/Page column 87-88 ;
  • Route3
    • 2-Bromo-5-fluoro-N-methoxy-N-methylbenzamide|CS-1222864
      313547-14-7
    • null|null
      75-16-1
    • ~97%
    • In-stock
      2'-Bromo-5'-fluoroacetophenone|CS-0019646
      1006-33-3

    References

    • Thome, Isabelle; Besson, Claire; Kleine, Tillmann; Bolm, Carsten Angewandte Chemie - International Edition, 2013 , vol. 52, # 29 p. 7509 - 7513 Angew. Chem., 2013 , vol. 125, # 29 p. 7657 - 7661,5

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.7908
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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