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Structure of 1004775-33-0
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This boronic acid features a trifluoromethyl group that enhances metabolic stability and lipophilicity, while the methoxy substituent fine-tunes electronic properties. The pendant boronate moiety enables efficient Suzuki-Miyaura cross-coupling under standard conditions, delivering arylated products with high fidelity.
(3-Methoxy-4-(trifluoromethyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the methoxy substituent provides moderate electron donation, improving reaction kinetics. The boronic acid exhibits good bench stability, facilitates straightforward purification via recrystallization or flash chromatography, and demonstrates broad functional group tolerance in standard coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: