Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(3-Methoxy-4-(trifluoromethyl)phenyl)boronic acid

  • CAS No. 1004775-33-0

  • Cat. No. CS-0150546
  • Purity≥98%
  • MDL No.MFCD13194426

*For research and further manufacturing use only, not for direct human use.

(3-Methoxy-4-(trifluoromethyl)phenyl)boronic acid|CS-0150546

Structure of 1004775-33-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1004775-33-0
  • Cat. No. CS-0150546
  • Purity ≥98%
  • MDL No. MFCD13194426
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BF₃O₃
  • Molecular Weight 219.95
  • Synonym(s) 3-Methoxy-4-(trifluoromethyl)phenylboronic acid
  • SMILES COC1=C(C=CC(=C1)B(O)O)C(F)(F)F

Description

This boronic acid features a trifluoromethyl group that enhances metabolic stability and lipophilicity, while the methoxy substituent fine-tunes electronic properties. The pendant boronate moiety enables efficient Suzuki-Miyaura cross-coupling under standard conditions, delivering arylated products with high fidelity.

Application

(3-Methoxy-4-(trifluoromethyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the methoxy substituent provides moderate electron donation, improving reaction kinetics. The boronic acid exhibits good bench stability, facilitates straightforward purification via recrystallization or flash chromatography, and demonstrates broad functional group tolerance in standard coupling protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   49.69
  • LogP   0.3938
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1004775-33-0 sigma1004775-33-0 manufacturer1004775-33-0 price1004775-33-0 structure1004775-33-0 SDSbuy 1004775-33-01004775-33-0 supplier1004775-33-0 uses1004775-33-0 molecular weightprice of 1004775-33-01004775-33-0 chemical name formula of 1004775-33-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label