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Structure of 1003846-21-6
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This pyrazole boronate ester integrates a tetrahydropyranyl protecting group and a stable dioxaborolane moiety, enabling orthogonal functionalization in complex synthesis. The bench-stable, moisture-tolerant structure facilitates reliable cross-coupling under standard conditions.
1-(Tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetrahydropranyl (THP) ether protects the pyrazole nitrogen, enabling orthogonal handling in complex syntheses. The pinacol boronate group facilitates reliable coupling with aryl and heteroaryl halides under mild conditions, offering high functional group tolerance and ease of purification—ideal for constructing biaryl scaffolds in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: