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Structure of 1003711-04-3
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2-Amino-5-fluoropyridin-3-ol features a strategically positioned amino group and fluorine atom on a pyridinol scaffold, enabling strong hydrogen bonding and enhanced metabolic stability. This electron-deficient heterocycle integrates readily into bioactive scaffolds, particularly in kinase inhibitors and pharmaceutical intermediates, where its dual functionalization supports efficient derivatization under standard conditions.
2-Amino-5-fluoropyridin-3-ol serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds. Its ortho-amino and hydroxyl groups facilitate diverse coupling reactions and metal-catalyzed transformations, while the fluorine substituent enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: